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Molecules 17 , 21402160 (2012)

One 2023 study in Circulation even found that clearing senescent cells, including with FOXO4-DRI, worsened pulmonary hypertension in rodents

Symptoms may include a sore throat, cheilosis (lesions on the lips), angular stomatitis (lesions on the angles of the mouth), glossitis (fissured and magenta-colored tongue), corneal vascularisation (very visible red veins in the whites of the eyes), dyssebacia (red, scaly, greasy patches on the nose, eyelids, scrotum, and labia), and anemia