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A pragmatic alternative is to prepare smaller vials from your reconstituted stock and freeze them as single-use aliquots at 20C, minimizing repeated freeze-thaw exposure to your main vial

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A double-blind comparison of clomipramine and desipramine treatment of severe onychophagia (nail biting)

It is also remembered that pharmacological formulations are required to improve to efficiently and safely use Lf-conjugated NPs and keep them at stable conditions for Lf conjugation