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The main metabolite, [ 3 H]proline (M1), accounted for 4.96% (female) and 3.93% (male) of the bile samples (Figure 5C)

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In the IR group, oxidant parameters (malondialdehyde (MDA), myeloperoxidase (MPO), total oxidant status (TOS), oxidative stress index (OSI)) increased, and antioxidant level parameters (superoxide dismutase (SOD) and total antioxidant status (TAS)) diminished

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SERD, selective estrogen receptor degrader

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