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Declaration of interest D Papamargaritis has acted as a speaker for Novo Nordisk and has received grants from Novo Nordisk, Novo Nordisk UK Research Foundation, Academy of Medical Sciences/Diabetes UK, Health Education East Midlands and the National Institute for Health and Care Research (NIHR)

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its most advanced clinical use, the CagriSema combination with semaglutide, remains under regulatory evaluation

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