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Targeting HSPs in autoimmune diseases HSP90 inhibition and inflammatory control HSP90 inhibitors have shown notable immunomodulatory activity in preclinical autoimmune models, consistent with the role of HSP90 in stabilizing signaling proteins that amplify immune activation

Retinoic acid regulates the nigrostriatal dopaminergic system [213] and receptor-mediated physiology in the adult brain [214]

Therefore, nutraceutical skin applications using collagen and antioxidants such as curcumin and glutathione demonstrate hopeful results for dermal antiaging effects, especially in estrogen-deficient skin

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