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Given the significant burden of these symptoms, depression is recognized as one of the most common and debilitating mental health conditions worldwide

Evaluation of drug biliary excretion using sandwich-cultured human hepatocytes

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Crucially, the progress and accessibility of potent, brain-permeable compounds that specifically target 7nAChR receptors, including agonists, allosteric agonists, partial agonists, and positive modulators, would greatly aid in conducting pre-clinical and clinical trials [48]