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PMID 18403632

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p-BSQ oxidized protein in the nitrogen atmosphere in the absence of molecular oxygen (4) indicating that there is a direct interaction of p-BSQ and biological macromolecules

The filter as claimed in claim 1, wherein the smoke containing very low level of p-BSQ is incapable of producing significant oxidative damage to the lung microsomal proteins of guinea pigs when said guinea pigs are exposed to smoke emitted from said charcoal-filtered tobacco smoke devices in contrast to marked damage of the lung tissue when the guinea pigs are exposed to smoke from tobacco smoke devices without having the charcoal filter