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If you want a plain-English look at who genuinely needs the vitamin, our companion piece on B12 injections covers that in full

8 weeks (~75 mg/day avg): ~9 vials 12 weeks: ~13 vials 16 weeks: ~17 vials Insulin Syringes (U-100, 1 mL) Per injection: 1 syringe 8 weeks (once daily): ~56 syringes 16 weeks (once daily): ~112 syringes Bacteriostatic Water (10 mL bottles) Use 5.0 mL per 500 mg vial for reconstitution

For the initial treatment of vitamin B12 deficiency, the usual dose is 100mcg SC/MC, given every day for 10-15 days, followed by maintenance treatment

These mechanisms are observed under controlled in vitro and in vivo experimental conditions where the peptide interacts with cellular and tissue systems