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Description

Agrawal V, Woo JH, Borthakur G , Kantarjian H, Frankel AE

Retinol dehydrogenases use NADPH as a cofactor in the reduction of retinaldehyde to retinol and use NAD + as cofactor when oxidizing retinol to retinaldehyde

NNMT is increased in a broad range of cancers, such as papillary thyroid cancer, renal clear cell carcinoma, glioblastoma tumors, bladder cancer, colorectal cancers, gastric cancers, and oral squamous cell carcinoma