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10.1016/j.bpc.2023.107122 Biophys

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Fan C et al (2024) Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis

Interestingly, the presence of tamoxifen and rotenone together produced the largest growth inhibitory effects on CHO R C5 that were reversed with the addition of NAC (0.5 mM) which increases reduced-thiols levels or PSC-833 (2 M), an inhibitor of P-gp-ATPase activity (Fig