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Drugs inhibiting their action can lead to the removal of senescent cells [101]

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Knockout or overexpression of PRMT1 in TECs can alleviate or aggravate CaOx-induced renal injury by regulating fatty acid metabolism TEC-specific PRMT1 overexpression mice were generated by injecting rAAV9 carrying either a TEC-specific Ksp promoter-driven PRMT1 construct (rAAV9-Ksp-PRMT1) or an empty vector (rAAV9-Ksp-null) into the bilateral kidneys using a microliter syringe to further evaluate the role of PRMT1