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All animals with fractures or skin ruptures were removed from the study

Psychiatric manifestations (sleep disturbances, anxiety, and depression) are also common and significantly increase in due course of neuro-PASC development 201

To address the aforementioned issues, clinical trials evaluating the synergistic effects of combined hormone and antioxidant therapies are required

Additionally, studies have demonstrated that removing the insulin receptor in mice decreases blood glucose levels in response to IGF-1, indicating that IGF-1 can compensate for insulin's role in glucose metabolism to some extent (Clemmons, 2004)