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Summary: Vitamin B12 supplements can be taken at any time of day, as absorption mechanisms function consistently throughout the 24-hour cycle, with consistency being more important than specific timing

Important: Patients with Leber hereditary optic neuropathy should not take methyl B12 shots

However, full effects on metabolism and other areas may take 4-6 weeks as it takes time for levels to build up in the body

CPT 96374, by contrast, covers intravenous (IV) push administration where the substance is delivered directly into a vein, typically by a syringe, and the administering provider must be present during the entire infusion