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Mice C57BL/6, TLR9 -/- , TLR2/9 -/- and ASK1 -/- mice [11], [53], [54] were bred at M&B Taconic (Laven, Denmark) and kept in the animal facility at The Faculty of Health Sciences, AU between the time of delivery (at 4 to 6 weeks of age) and the time of the experiments, and used for experiments between the age of 7 and 9 weeks old

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Myo-inositol and the ovarian function Through its effects on the calcium pathway, myo-inositol plays a direct and key role on the maturation of an oocyte (egg) which leads to better oocyte quality and increased ovulation rate (17-19)