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DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis

Statistical significance in a, g were determined by one-way ANOVA followed by Bonferroni post-hoc analysis

7.1 Iron chelators 7.1.1 Preclinical stage Natural and synthetic iron chelators in preclinical development exhibit neuroprotective potential by modulating cerebral iron dyshomeostasis, though their translational value requires further validation

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