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Atakhorrami M, Rahimi-Aliabadi S, Jamshidi J, Moslemi E, Movafagh A, Ohadi M, et al

Many supplement ingredients can increase thermogenesis, the process in which the body raises its temperature or energy output

It is proposed that the non-ubiquitinated NRF2 would remain bound to the KEAP1-Cul3 complex and therefore prevent the newly translated NRF2 from inhibition by the E3-ubiquitin complex, thereby promoting NRF2 accumulation in the nucleus [17]