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In this review, we summarize findings from clinical, animal models and in vitro studies that have elucidated the importance of the oxidative stress induced by smoking in different bone cells activities, leading bone mineral and organic matrix structural changes

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Although hypertension and diabetes appeared to be more common in smokers, there was no significant difference between the male smokers and non-smokers, while hypertension among females was actually more prevalent in non-smokers than in smokers