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These findings confirm that the absence of dose-response is robust to landmark conditioning

ATP5A) were higher in WT mice fed HF-SAAR compared to WT mice fed the HF-CTRL diet

47,51 This is consistent with the general finding that some DNA and RNA metabolizing modifying enzymes incorporate an FeS cluster, which modulates enzyme activity, and may well mediate long-range electron transport through the nucleic acid to regulate and coordinate enzyme activity during DNA replication and repair processes

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