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1 Introduction Inflammatory bowel disease (IBD) is a chronic, incurable disorder that poses low mortality, stable course, and recurrence, and is a global health problem whose incidence and prevalence are steadily increasing ( Patients with IBD were found to have an altered intestinal microenvironment, often correlated to higher reactive oxygen species (ROS) levels, leading to damage to the intestinal epithelial barrier and inflammatory response ( Recently, cell ferroptosis was found to be involved in the development of IBD

NNMT dysregulation is implicated across obesity, insulin resistance, liver pathology, and other disorders

Amble encourages users to promptly report any side effects or adverse reactions to a licensed healthcare provider and the pharmacy that dispensed the medication