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The initial definition of TAM subsets based on M1 (pro-inflammatory and tumor suppressing) and M2 (anti-inflammatory and promoting tumor progression) (35, 38, 39) was recently overcome by a more heterogenous definition based on transcriptional programs representative of different phenotypes and functions, including activation and cytokine production (4043)

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Such a clearcut increase confirms the working hypothesis that the adaptative reaction to oxidative stress in pregnancy includes the increase of GP enzyme antioxidant activity

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