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Malaguarnera M, Gargante MP, Russo C, Antic T, Vacante M, Malaguarnera M, Avitabile T, Li Volti G, Galvano F

Besides its use to remove copper from the body, DPA has also been used as an antidote for mercury and lead poisoning, especially before the clinical advent of DMSA and DMPS

This compound is a cyclic hydroxylamine that is oxidized upon the reaction with superoxide to generate a more stable radical called nitroxide

The Pro23His (P23H) variant is the most frequent mutation in the rhodopsin ( RHO )-encoding gene, and alone accounts for 10% of autosomal dominant RP cases in North America