can depression get worse after b12 injections Why do I feel a injection: causes explained Feeling worse after B12 Injection:

These adaptations may explain why metabolic benefits can continue to improve over weeks to months of consistent use, rather than plateauing immediately

The various forms of injectable B12 have slightly different properties that impact how you might respond: Cyanocobalamin is the most synthesized and stable type but has to convert to active forms

Methionine in turn is required for the synthesis of S-adenosylmethionine, a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA, RNA, and proteins ( Figure 1 ) (3)

We also know that the serum B12 test is inaccurate and cannot tell us what is happening at a cellular level