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Safety, tolerability, and activity of ALXN1830 targeting the neonatal Fc receptor in chronic pemphigus

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The glutathione analogues were also screened at a concentration of 100 M each in the in vitro assay, but surprisingly all of them proved to be ineffective as inhibitors against the ChaC1 enzyme (Figure S2)

Furthermore, the intestinal mucosa hosts a very large immune system called gut-associated lymphoid tissue (GALT) that is in close contact with the microbiota and controls its potentially pathogenic strains