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Testing was conducted by Swift Laboratory, an ISO 17025:2017-accredited third-party testing facility (ANAB Certificate No

The scheduled MRM window was 60 sec, optimized oxylipin parameters were adopted 115 , and the curtain gas pressure was set to 35 psi

However, this was not a controlled trial there was no placebo group, and the assessments were informal (patient surveys by phone)

Complementing these targeted analyses, a recent epigenome-wide association study demonstrated sex-specific DNA methylation changes and epigenetic age acceleration, including the differential methylation in both CRY2 and RORA, linking NSW to epigenetic alterations in circadian regulators 33