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Current FDA approved pharmaceutical treatment for acute ischemia is limited to thrombolytic intervention, which functions to restore blood flow, yet patients often still suffer long term motor, behavioral, and cognitive deficits due to a lack of interventions focused on promoting neuronal post-stroke recovery (Stubblefield and Lechleiter, 2019)

Extended follow-up studies would identify any delayed adverse effects and establish whether therapeutic benefits persist, diminish, or require continued treatment for maintenance

Hydroxocobalamin, however, is the most biologically active form of Vitamin B12