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Continued research and well-designed clinical trials are essential to validate its benefits and ensure its safe application in medical practice

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Cadmium exerts multiple detrimental effects on reproductive health through various mechanisms, including disruption of the HPG axis, structural damage to the blood-testis barrier and testicular vasculature

Consistent with the results observed in in vivo experiments, GHK-Cu significantly restored Nrf2 expression in the cytoplasm and reduced it in the nucleus while significantly reducing Keap1 levels in the cytoplasm compared with the CSE-exposed cells without GHK-Cu (Figures 6DF)