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Description

The NOX-generated superoxide can be converted to other forms of ROS or detoxified by reduced glutathione and glutathione-coupled antioxidant enzymes, such as glutathione peroxidases (GPXs) and glutathione reductase (GR), to maintain redox homeostasis

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Also, this strategy of bending the implant during surgery prompts the creation of multiple scratches and notches on the implant surface, which may favor adhesion formation to adjacent tissues and may exacerbate allergies to the standard stainless surgical steel bar.[80] Park et al.[96] suggested a patient-specific approach based on anthropometric/morphologic assessments of the patients chest wall, but ultimately this technique still relied on surgeon experience

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