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Lung disease research has explored GHK-Cu for idiopathic pulmonary fibrosis and COPD, with animal studies showing reduced fibrosis and improved lung function

In a murine model of melanoma overexpressing IL-12 (B16-IL-12), NKp46 + ILC3 were shown to infiltrate the tumor and mediate the upregulation of ICAM-1 and VCAM-1 adhesion molecules on tumor vessels leading to the generation of a pro-inflammatory microvascular environment (123)

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