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Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge
Storage: Lyophilized recombinant Mouse MCP-5/CCL12 remains stable up to 6 months at -80°C from date of receipt
Engagement of TCR complex with foreign antigens induces tyrosine phosphorylation in the ITAM motifs and phosphorylated ITAMs function as docking sites for signaling molecules such as ZAP-70 and p85 subunit of PI-3 kinase
Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells
SCIN Monoclonal Antibody-MB11572 Size:50µl Participates in the regulation ofSCIN Monoclonal Antibody Sizes: 50l, 100l Catalogue Numbers: MB11572 50, MB11572 100 Product: 50mM Tris Glycine(pH 7. 4), 0. 15M NaCl, 40% Glycerol, 0. 01% Sodium azide and 0. 05% BSA Swiss Prot: Q9Y6U3 Host: Rabbit Reactivity: Human Applications: WB, IHC P All Applications: WB: 1 500 1 1000 IHC: 1 50 1 100 Background: Ca2+ dependent actin filament severing protein that has a regulatory function in exocytosis by affecting the organization of the