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The body needs additional oxygen, and nicotine speeds up the heart rate

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This makes it more difficult for the lungs to expel dust and mucus, which frequently results in severe asthma-COPD overlap syndrome or COPD

Here we investigated 136 variables and identified smoking, cytomegalovirus latent infection and body mass index as major contributors to variability in cytokine response, with effects of comparable magnitudes with age, sex and genetics