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Interventions targeting the oral and gut microbiota include specific dietary patterns, taking prebiotics/probiotics, undergoing microbial transplantation, using antibiotics, and utilizing other medicines 147,148 (Fig

(Basel) 15, 1296

Anti-anxiety effects in rats at 0.5 g/kg (extremely low dose) produced effects within 12 minutes of intraperitoneal injection, including increased time exploring open/lighted maze areas, decreased immobile freeze reaction time, and increased exploration in open field tests

Administration methods Injectable peptides are most common, with subcutaneous injection being standard for most compounds