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GHK-Cu (glycyl-L-histidyl-L-lysine-copper) is a naturally occurring tripeptide-copper complex first identified in human blood plasma in 1973 by Dr

It originates from either side of the medulla oblongata, exits through the jugular foramen, and descends the neck, chest, and abdomen (Liu and Forsythe, 2021)

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Moreover, supplementation with Lactobacillus plantarum (DP189) and GOS restored gut microbial composition, improved gut and BBB integrity, reduced cortical inflammation and elevated acetylcholinesterase activity, reversing anxiety and depression-like behaviors in mice (Wang J