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The therapy is in two phases: an initial therapy with the aim of removing the accumulated copper, followed by a maintenance therapy with the aim of preventing a new copper accumulation

Proc Natl Acad Sci USA 110:1862018625 Oliveira SH, Fonseca SG, Romao PR, Figueiredo F, Ferreira SH, Cunha FQ (1998) Microbicidal activity of eosinophils is associated with activation of the arginine-NO pathway

71 A review of nonpharmacological interventions for people with dementia found that the strongest evidence for reducing responsive behaviors (behaviors in response to sensations such as pain, hunger, thirst, fatigue, and feeling too hot or too cold) involved music, sensory stimulation, simulated presence and validation therapies

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