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Sustained use is what trial protocols approximate

Arginine may help alleviate stroke-like episodes in patients with COX-deficient MELAS, while coenzyme Q10 has shown promise in slowing disease progression in COX4I1 deficiency (16, 104)

Our results that NAC increased plasma citrulline concentrations and attenuated the decrease in D-xylose concentrations in the plasma of -CG-challenged piglets indicated improvements in intestinal mass/metabolic activity and absorptive function in response to oral administration of NAC

The Bottom Line When you have chest pain, especially if the pain is severe and persistent, talk to your doctor or call for medical help