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blood pressure effects with retatrutide vary and should be monitored clinically [18] [17] Hormonal dysregulation disruption of the hypothalamic-pituitary axis Infection risk from non-sterile self-injection practices Harmful patterns of use reliance on unregulated compounds in pursuit of perceived performance or aesthetic benefits, without medical supervision Red-flag symptoms requiring urgent medical attention include severe or persistent abdominal pain (which may radiate to the back), persistent vomiting, signs of jaundice (yellowing of the skin or eyes), symptoms of dehydration, palpitations, or signs of an allergic reaction

The authors are grateful to the Medical College of Georgia-Augusta University Research Administration for funding support of this work

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Shen HM, Pervaiz S