All of them are molecules that modulate the dynamics of the cytoskeleton, and in particular, MLC collaborates in the interactions of actin and myosin filaments [63] , enabling cellular movement of the cytoskeleton
TRPV1 is also activated by capsaicin (hot peppers), low extracellular pH, and noxious heat.[ref] TRPA1 is activated by VOCs, cigarette smoke, heavy metals, naphthalene (moth balls), formaldehyde, and styrene.[ref] TRP receptors are highly expressed in the olfactory and trigeminal nerve endings and in the brain
Oral pills are also a viable option, but they rank slightly below sprays in terms of absorption potential
Krehelova A, Kovarikova V, Domorakova I, et al