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In cardiomyocytes, BRG1 and BRM maintain mitophagy and mitochondrial function by regulating genes such as MFN1, DNM1L , and PINK1 , thereby preserving cell viability under metabolic stress

In addition to OGG1, MUTYH is responsible for repairing oxidative DNA damage by removing adenine, which is incorrectly inserted across 8oxoG

Approximately 5% of the inhaled O 2 is converted to reactive oxygen molecules with an unpaired number of electrons such as hydroxyl (OH), superoxide anion (O 2 -), hydrogen peroxide (H 2 O 2 ), oxygen singlet (O 2 ), hypochlorite (OCI-), nitric oxide (NO), and peroxynitrite (ONOO-) radicals

Both compounds are administered subcutaneously, typically in the abdomen, thigh, or upper arm