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The clinical picture varies substantially between individuals the woman with severe insulin resistance and obesity faces a different therapeutic priority than the lean woman with a GnRH pulse disorder and normal metabolic indices and treatment should reflect that heterogeneity

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Adebayo AS, Agbaje K, Adesina SK, Olajubutu O (2023) Colorectal cancer, disease process, current treatment options, and future perspectives

NREM sleep itself is categorized in three stages based on brain wave activity 15,16 : Stage 1 (N1) is when the body is transitioning to sleep