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Procurement teams generally evaluate suppliers on documentation depth, RUO compliance, and analytical transparency

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Groups at higher risk of deficiency include older adults (due to reduced stomach acid production), vegans and vegetarians, people with pernicious anaemia or gastrointestinal disorders affecting absorption, and those taking certain medications such as metformin or proton pump inhibitors

Figure 2 and Table 1 summarize the primary disease domains influenced by probiotics, including GI, metabolic, infectious, oncological, and neuropsychiatric indications