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Linus Pauling Institute Oregon State University Updated in October 2018 by: Barbara Delage, Ph.D

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They included 668 patients with 2,231 SSC and 1,036 patients with 1,175 cancers other than SCC

In studies of human glioblastoma, the absence of exogenous Gln significantly reduces glutamate levels, resulting in the conversion of the dimer GLS1 into a self-assembled, extremely low Km filamentous polymer that further depletes intracellular Gln