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The toxic effects of ROS are mitigated by antioxidant enzymes, including catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase (SOD), as well as non-enzymatic antioxidants such as glutathione (GSH), vitamins C and E, and uric acid

Combating resistance to anti-IGFR antibody by targeting the integrin 3-Src pathway

Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

Consistently, pharmacological inhibition of FMO3 with DIM or methimazole (MMI) largely abrogated LPS + TMA-induced TMAO production and inflammasome activation (reflected by caspase-1 activity and IL-1 in medium) in 3T3-L1 mature adipocytes (Supplementary Fig