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A higher risk of deficiency is present in patients with malabsorptive syndrome and/or unusually low sun exposure, those who have undergone gastric bypass surgery, or those on prolonged glucocorticoid use (which alters intestinal absorption) ( Cancer patients may have a higher risk of deficiency due to causes of intestinal fat malabsorption (i.e., intestinal surgery, pancreatectomy, gastrectomy) or due to oncologic treatments, such as aromatase inhibitors

Shock 28 : 484490 Urata Y, Ihara Y, Murata H, Goto S, Koji T, Yodoi J, Inoue S, Kondo T 2006 17-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells

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Why does OROS Research perform testing beyond purity