DAPT Pack Size:10 mM * 1 mL in DMSO rheumatoid arthritis

rheumatoid arthritis

promotes Ig class-switching and plasma cell differentiation

selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM

Bafilomycin A1 induces apoptosis

DAPT Pack Size:10 mM * 1 mL in DMSO rheumatoid arthritisDAPT (GSI IX) is a potent and orally active secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid (A) and A42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment.