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By employing LC-MS/MS technology, we can precisely identify all our analytes, reducing the risk of false positives

Ocitinib-resistant cells can enhance glucose and Gln uptake, while inhibiting Gln uptake and metabolism in NSCLC, effectively reducing the proliferation of ocitinib resistant cells and promoting cell apoptosis (27)

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Thus, all three of the main UA transporters may contribute to the brain concentrations of UA through their action at the blood-brain barrier, although ABCG2 is thought to have the greatest effect, probably acting to remove UA from brain to blood 45