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When tirzepatide binds to GIP receptors on pancreatic beta cells, it enhances glucose-stimulated insulin secretion without causing hypoglycemia

10.1016/j.bbagen.2013.02.017 9 BozinovskiS.SeowH

Ann Rev Physiol

However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached