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Aged recipients of SIRT3-overexpressing HSCs (T3 Tx) exhibited reduced numbers of CD68 + macrophages, F4/80 + tissue-resident macrophages, and CCR2 high inflammatory monocytes in the tissues, compared to mice transplanted with control HSCs (Cre Tx) (Extended Data Fig

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The residual GSH concentration in MG003 was also high (6.9 0.20 mM), which was 2.1-fold that of in E