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Hypothelamic-Pituitary-Adrenal Axis Tumors of the cortisol-secreting cells of the adrenal cortex secrete excessive cortisol, resulting in excessive tissue protein degradation and muscle wasting Cushing's syndrome As a source of energy, amino acid carbon skeletons are directly oxidized, or, in the starved state, converted to glucose and ketone bodies, and then oxidized

Optical nanomaterial-based detection of biomarkers in liquid biopsy

De-Haan, J.B., Cristiano, F., Innello, R.C

EXPERIMENTAL Animals The experiments were conducted using 60 male APPswe/PS1dE9/Blg (APP/PS1) mice with a mixed C57Bl6/Chg genetic background and 20 male C57Bl6/Chg (wild-type, WT) mice