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The underpinning of retinitis pigmentosa lies in inherited or spontaneous mutations, culminating in a gradual demise of photoreceptor cells (predominantly rods) and concurrent RPE deterioration [342]

They found a half-life of under 30 minutes post-injection, with bioavailability after intramuscular administration at 14 to 19 percent for rats and 45 to 51 percent for dogs

doi: 10.4103/ijot.ijot_8_18 [DOI] [PMC free article] [PubMed] [Google Scholar] 84.Liu D, Xu Q, Meng X, Liu X, Liu J