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Supplementation with carnitine at a dosage of 2 g/day for 4 weeks in patients with impaired glucose metabolism was associated with a significant reduction of insulin levels and HOMA-IR score

Oxygen is important in ATP generation process, which is responsible for energy support used during normal CNS function

A growing body of preclinical research suggests that targeting the ferroptosis regulatory pathway centered on GPX4, including drug inhibitors, natural active compounds, gene or RNA intervention strategies, and novel local delivery systems, can alleviate cartilage degeneration and joint inflammation to varying degrees in experimental OA models

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