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The exclusion criteria included review articles, duplicate articles, patents, abstracts, conference papers, and studies with no in vivo investigations

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There is some evidence to suggest that zonation associated with P450 induction is modulated by circulating levels of growth hormone and thyroid hormones, whereas the zonation of constitutive P450 expression is governed by other factors (Lindros 1997

195 In terms of clinical intervention, Jianpi Shugan formula combined with lifestyle intervention for 12 weeks in NAFLD patients significantly improved liver function, liver stiffness, and glucolipid metabolism compared to lifestyle intervention alone